Generic Acomplia (Rimonabant)

Diet pill Acomplia is a miraculous multifunctional pill that helps you short out obesity as well as smoking. Acomplia diet pills work on the Endocannabinoid system, which controls appetite and energy expenditure (as well as the urge to smoke). This wonder pill selectively blocks some receptors in the Endocannabinoid system, thus creating a better balance which in turn suppresses appetite and the longing to overeat.

How does Acomplia work?
• Acomplia acts by selectively blocking CB1 receptors found in the brain and in peripheral organs important in glucose and lipid (or fat) metabolism, including adipose tissue, the liver, gastrointestinal tract and muscle1.
• Acomplia switches off the same brain circuits that make people hungry when they smoke cannabis.
• CB1 receptor blockade with Acomplia acts to decrease the overactivity of the endocannabinoid system (EC system)2,3. The EC system is a recently characterised physiological system that includes receptors such as the CB1 receptor and it has been shown to play an important role in regulating body weight and in controlling energy balance, as well as glucose and lipid (or fat) metabolism.

Does Acomplia also aid smoking cessation?
• Acomplia has been studied by sanofi-aventis as an aid to smoking cessation based on studies for up to one year in over 6,500 smokers motivated to quit smoking.
• Sanofi-aventis submitted a New Drug Application to the FDA, which in turn issued a non approvable letter for Acomplia for use in smoking cessation. An approvable letter was however issued for Acomplia for use in weight management.
Acomplia has just been approved in the European Union. Is Acomplia approved in the United States?
• No. Sanofi is still awaiting U.S. marketing go-ahead which it has said could come by the end of this year.
• U.S. health authorities have asked Sanofi for more information on Acomplia.
• Acomplia received European Union marketing approval in June 2006.

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